Reaction Details Report a problem with these data
Target
Prostaglandin D2 receptor
Ligand
BDBM50351495
Substrate
n/a
Meas. Tech.
ChEMBL_764675 (CHEMBL1821227)
Ki
12±n/a nM
Citation
 Iwahashi, M; Takahashi, E; Tanaka, M; Matsunaga, Y; Okada, Y; Matsumoto, R; Nambu, F; Nakai, H; Toda, M Design and synthesis of new prostaglandin D2 receptor antagonists. Bioorg Med Chem 19:5361-71 (2011) [PubMed]  Article 
Target
Name:
Prostaglandin D2 receptor
Synonyms:
PD2R_MOUSE | Prostanoid DP receptor | Ptgdr
Type:
PROTEIN
Mol. Mass.:
40018.63
Organism:
Mus musculus
Description:
ChEMBL_788408
Residue:
357
Sequence:
MNESYRCQTSTWVERGSSATMGAVLFGAGLLGNLLALVLLARSGLGSCRPGPLHPPPSVFYVLVCGLTVTDLLGKCLISPMVLAAYAQNQSLKELLPASGNQLCETFAFLMSFFGLASTLQLLAMAVECWLSLGHPFFYQRHVTLRRGVLVAPVVAAFCLAFCALPFAGFGKFVQYCPGTWCFIQMIHKERSFSVIGFSVLYSSLMALLVLATVVCNLGAMYNLYDMHRRQRHYPHRCSRDRAQSGSDYRHGSLHPLEELDHFVLLALMTVLFTMCSLPLIYRAYYGAFKLENKAEGDSEDLQALRFLSVISIVDPWIFIIFRTSVFRMLFHKVFTRPLIYRNWSSHSQQSNVESTL
  
Inhibitor
Name:
BDBM50351495
Synonyms:
CHEMBL1819620
Type:
Small organic molecule
Emp. Form.:
C26H25ClN2O5
Mol. Mass.:
480.94
SMILES:
CN1C[C@@H](COc2ccc(C(=O)Nc3cc(C)cc(CC(O)=O)c3)c(Cl)c2)Oc2ccccc12 |r|
Structure:
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