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Target
Prostaglandin E2 receptor EP1 subtype
Ligand
BDBM50360151
Substrate
n/a
Meas. Tech.
ChEMBL_793557 (CHEMBL1932308)
Ki
>10000±n/a nM
Citation
 Kambe, T; Maruyama, T; Nagase, T; Ogawa, S; Minamoto, C; Sakata, K; Maruyama, T; Nakai, H; Toda, M Synthesis and evaluation of novel modified¿-lactam prostanoids as EP4 subtype-selective agonists. Bioorg Med Chem 20:702-13 (2012) [PubMed]  Article 
Target
Name:
Prostaglandin E2 receptor EP1 subtype
Synonyms:
PE2R1_MOUSE | PGE receptor, EP1 subtype | Prostaglandin E1 | Prostaglandin E2 receptor EP1 subtype | Prostanoid EP1 receptor | Ptger1 | Ptgerep1
Type:
G-protein coupled receptor
Mol. Mass.:
43000.62
Organism:
Mus musculus (Mouse)
Description:
n/a
Residue:
405
Sequence:
MSPCGLNLSLADEAATCATPRLPNTSVVLPTGDNGTSPALPIFSMTLGAVSNVLALALLAQVAGRMRRRRSAATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALAVLAAMALAVALLPLVHVGRYELQYPGTWCFISLGPRGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRKTAGPDDRRRWGSRGPRLASASSASSITSATATLRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELGLTKSAWEASSLRSSRHSGFSHL
  
Inhibitor
Name:
BDBM50360151
Synonyms:
CHEMBL1929543
Type:
Small organic molecule
Emp. Form.:
C19H24FNO4S2
Mol. Mass.:
413.527
SMILES:
O[C@@H](Cc1cccc(F)c1)\C=C\[C@H]1CSC(=O)N1CCSCCCC(O)=O |r|
Structure:
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