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Target
Delta-type opioid receptor
Ligand
BDBM50280516
Substrate
n/a
Meas. Tech.
ChEBML_217856
Ki
2090±n/a nM
Citation
 Rajagopalan, P; Scribner, R; Pennev, P; Schmidt, W; Tam, S; Steinfels, G; Cook, L DuP 747: a new, potent, kappa opioid analgesic. Synthesis and pharmacology1. Bioorg Med Chem Lett 2:715-720 (1992)    Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50280516
Synonyms:
2-(3,4-Dichloro-phenyl)-N-((1S,2S)-5-methoxy-2-pyrrolidin-1-yl-1,2,3,4-tetrahydro-naphthalen-1-yl)-N-methyl-acetamide; compound with methanesulfonic acid | CHEMBL350943
Type:
Small organic molecule
Emp. Form.:
C24H28Cl2N2O2
Mol. Mass.:
447.397
SMILES:
COc1cccc2[C@@H]([C@H](CCc12)N1CCCC1)N(C)C(=O)Cc1ccc(Cl)c(Cl)c1
Structure:
Search PDB for entries with ligand similarity: