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Target
Mu-type opioid receptor
Ligand
BDBM50280515
Substrate
n/a
Meas. Tech.
ChEBML_222066
Ki
545±n/a nM
Citation
 Rajagopalan, P; Scribner, R; Pennev, P; Schmidt, W; Tam, S; Steinfels, G; Cook, L DuP 747: a new, potent, kappa opioid analgesic. Synthesis and pharmacology1. Bioorg Med Chem Lett 2:715-720 (1992)    Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50280515
Synonyms:
2-(3,4-Dichloro-phenyl)-N-methyl-N-((1S,2S)-2-pyrrolidin-1-yl-1,2,3,4-tetrahydro-naphthalen-1-yl)-acetamide; hydrochloride | CHEMBL538806
Type:
Small organic molecule
Emp. Form.:
C23H26Cl2N2O
Mol. Mass.:
417.371
SMILES:
CN([C@@H]1[C@H](CCc2ccccc12)N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 |r|
Structure:
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