Reaction Details Report a problem with these data
Target
Serine protease 1
Ligand
BDBM50289377
Substrate
n/a
Meas. Tech.
ChEBML_212327
pH
7.5±n/a
Ki
1700±n/a nM
Comments
extracted
Citation
 von der Saal, W; Kucznierz, R; Leinert, H; Engh, RA DERIVATIVES OF 4-AMINO-PYRIDINE AS SELECTIVE THROMBIN INHIBITORS Bioorg Med Chem Lett 7:1283-1288 (1997)    Article 
Target
Name:
Serine protease 1
Synonyms:
Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I
Type:
Enzyme
Mol. Mass.:
25790.52
Organism:
Bos taurus (bovine)
Description:
P00760
Residue:
246
Sequence:
MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN
  
Inhibitor
Name:
BDBM50289377
Synonyms:
4-{3-[2-(4-Chloro-benzenesulfonylamino)-ethyl]-phenoxymethyl}-benzamidine | CHEMBL24827
Type:
Small organic molecule
Emp. Form.:
C22H22ClN3O3S
Mol. Mass.:
443.946
SMILES:
NC(=N)c1ccc(COc2cccc(CCNS(=O)(=O)c3ccc(Cl)cc3)c2)cc1
Structure:
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