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Target
Muscarinic acetylcholine receptor M1
Ligand
BDBM50291593
Substrate
n/a
Meas. Tech.
ChEBML_139961
Ki
1590±n/a nM
Citation
 Hudkins, RL; DeHaven-Hudkins, DL; Doukas, P Design of dual acting anticonvulsant-antimuscarinic succinimide and hydantoin derivatives Bioorg Med Chem Lett 7:979-984 (1997)    Article 
Target
Name:
Muscarinic acetylcholine receptor M1
Synonyms:
ACM1_RAT | Cholinergic, muscarinic M1 | Chrm-1 | Chrm1 | cholinergic receptor, muscarinic 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51390.46
Organism:
RAT
Description:
P08482
Residue:
460
Sequence:
MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
  
Inhibitor
Name:
BDBM50291593
Synonyms:
1'-(4-tetrahydro-1H-1-pyrrolyl-2-butynyl)spiro[2,3-dihydro-1H-indene-1,3'-(tetrahydro-1'H-pyrrole)]-2',5'-dione | CHEMBL177259
Type:
Small organic molecule
Emp. Form.:
C20H22N2O2
Mol. Mass.:
322.4009
SMILES:
O=C1CC2(CCc3ccccc23)C(=O)N1CC#CCN1CCCC1
Structure:
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