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Target
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B
Ligand
BDBM50106047
Substrate
n/a
Meas. Tech.
ChEBML_161774
IC50
810±n/a nM
Citation
 McCluskey, A; Walkom, C; Bowyer, MC; Ackland, SP; Gardiner, E; Sakoff, JA Cantharimides: a new class of modified cantharidin analogues inhibiting protein phosphatases 1 and 2A. Bioorg Med Chem Lett 11:2941-6 (2001) [PubMed]  Article 
Target
Name:
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B
Synonyms:
Serine-threonine protein phosphatase 2A regulatory subunit
Type:
PROTEIN
Mol. Mass.:
49694.81
Organism:
Gallus gallus
Description:
ChEMBL_161937
Residue:
426
Sequence:
DDDVAEADIISTVEFNHCGELLATGDKGGRVVIFQQEQENKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDSLDFNKKILHHAWHPKENIIAVATTNNLYIFQDKMN
  
Inhibitor
Name:
BDBM50106047
Synonyms:
(R)-2-((1S,2R,6S,7R)-3,5-Dioxo-10-oxa-4-aza-tricyclo[5.2.1.0*2,6*]dec-4-yl)-3-(3H-imidazol-4-yl)-propionic acid | CHEMBL100935
Type:
Small organic molecule
Emp. Form.:
C14H15N3O5
Mol. Mass.:
305.286
SMILES:
OC(=O)[C@@H](Cc1cnc[nH]1)N1C(=O)[C@H]2[C@@H]3CC[C@@H](O3)[C@H]2C1=O
Structure:
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