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Target
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B
Ligand
BDBM50451451
Substrate
n/a
Meas. Tech.
ChEMBL_198006 (CHEMBL798983)
IC50
3400±n/a nM
Citation
 McCluskey, A; Keane, MA; Walkom, CC; Bowyer, MC; Sim, AT; Young, DJ; Sakoff, JA The first two cantharidin analogues displaying PP1 selectivity. Bioorg Med Chem Lett 12:391-3 (2002) [PubMed]  Article 
Target
Name:
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B
Synonyms:
Serine-threonine protein phosphatase 2A regulatory subunit
Type:
PROTEIN
Mol. Mass.:
49694.81
Organism:
Gallus gallus
Description:
ChEMBL_161937
Residue:
426
Sequence:
DDDVAEADIISTVEFNHCGELLATGDKGGRVVIFQQEQENKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDSLDFNKKILHHAWHPKENIIAVATTNNLYIFQDKMN
  
Inhibitor
Name:
BDBM50451451
Synonyms:
CI-920 | Fostriecin Sodium
Type:
Small organic molecule
Emp. Form.:
C19H26NaO9P
Mol. Mass.:
452.3679
SMILES:
[Na+].CC(O)(\C=C\C1CC=CC(=O)O1)C(CC(O)\C=C\C=C\C=C\CO)OP(O)([O-])=O |c:7|
Structure:
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