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Target
Peroxisome proliferator-activated receptor gamma
Ligand
BDBM50132575
Substrate
n/a
Meas. Tech.
ChEMBL_154356 (CHEMBL759117)
Ki
8530±n/a nM
Citation
 Adams, AD; Hu, Z; von Langen, D; Dadiz, A; Elbrecht, A; MacNaul, KL; Berger, JP; Zhou, G; Doebber, TW; Meurer, R; Forrest, MJ; Moller, DE; Jones, AB O-arylmandelic acids as highly selective human PPAR alpha/gamma agonists. Bioorg Med Chem Lett 13:3185-90 (2003) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor gamma
Synonyms:
NR1C3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG | PPARG_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor gamma (PPAR gamma) | Peroxisome proliferator-activated receptor gamma (PPARG) | Peroxisome proliferator-activated receptor gamma (PPARĪ³) | Peroxisome proliferator-activated receptor gamma/Nuclear receptor corepressor 2 | peroxisome proliferator-activated receptor gamma isoform 2
Type:
Nuclear Receptor
Mol. Mass.:
57613.46
Organism:
Homo sapiens (Human)
Description:
P37231
Residue:
505
Sequence:
MGETLGDSPIDPESDSFTDTLSANISQEMTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY
  
Inhibitor
Name:
BDBM50132575
Synonyms:
4-(Carboxy-phenyl-methoxy)-3-chloro-5-propyl-benzoic acid methyl ester | CHEMBL320925
Type:
Small organic molecule
Emp. Form.:
C19H19ClO5
Mol. Mass.:
362.804
SMILES:
CCCc1cc(cc(Cl)c1OC(C(O)=O)c1ccccc1)C(=O)OC
Structure:
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