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Target
Sphingosine 1-phosphate receptor 5
Ligand
BDBM50133418
Substrate
n/a
Meas. Tech.
ChEMBL_201455 (CHEMBL807600)
EC50
1606±n/a nM
Citation
 Clemens, JJ; Davis, MD; Lynch, KR; Macdonald, TL Synthesis of para-alkyl aryl amide analogues of sphingosine-1-phosphate: discovery of potent S1P receptor agonists. Bioorg Med Chem Lett 13:3401-4 (2003) [PubMed]  Article 
Target
Name:
Sphingosine 1-phosphate receptor 5
Synonyms:
EDG8 | Endothelial differentiation sphingolipid G-protein-coupled receptor 8 | S1P5 | S1PR5 | S1PR5_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-8
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
41796.42
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
398
Sequence:
MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALTASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLDACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRARRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSLLNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSFSGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
  
Inhibitor
Name:
BDBM50133418
Synonyms:
CHEMBL423691 | Phosphoric acid mono-((S)-2-amino-2-tetradecylcarbamoyl-ethyl) ester; TFA
Type:
Small organic molecule
Emp. Form.:
C17H37N2O5P
Mol. Mass.:
380.4598
SMILES:
CCCCCCCCCCCCCCNC(=O)[C@@H](N)COP(O)(O)=O
Structure:
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