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Target
Sodium- and chloride-dependent creatine transporter 1
Ligand
BDBM50147101
Substrate
n/a
Meas. Tech.
ChEBML_49277
Ki
>10000000±n/a nM
Citation
 Geldenhuys, WJ; Lockman, PR; McAfee, JH; Fitzpatrick, KT; Van der Schyf, CJ; Allen, DD Molecular modeling studies on the active binding site of the blood-brain barrier choline transporter. Bioorg Med Chem Lett 14:3085-92 (2004) [PubMed]  Article 
Target
Name:
Sodium- and chloride-dependent creatine transporter 1
Synonyms:
CHOT1 | CT1 | Creatine transporter | Creatine transporter 1 | SC6A8_RAT | Slc6a8 | Sodium- and chloride-dependent creatine transporter 1 | Solute carrier family 6 member 8
Type:
PROTEIN
Mol. Mass.:
70632.63
Organism:
Rattus norvegicus
Description:
ChEMBL_49276
Residue:
635
Sequence:
MAKKSAENGIYSVSGDEKKGPLIVSGPDGAPSKGDGPAGLGAPSSRLAVPPRETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEISLGQFMKAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWNTPDCVEIFRHEDCANASLANLTCDQLADRRSPVIEFWENKVLRLSTGLEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPGALDGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILALINSGTSFFAGFVVFSILGFMATEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTDGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFFTPLVCMGIFIFNVVYYKPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGCLLRAKGTMAERWQHLTQPIWGLHHLEYRAQDADVRGLTTLTPVSESSKVVVVESVM
  
Inhibitor
Name:
BDBM50147101
Synonyms:
1-(1-Ethyl-1,2,3,6-tetrahydro-pyridin-4-yl)-ethanone | CHEMBL104154
Type:
Small organic molecule
Emp. Form.:
C9H15NO
Mol. Mass.:
153.2215
SMILES:
CCN1CCC(=CC1)C(C)=O |c:5|
Structure:
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