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Target
Alpha-1A adrenergic receptor
Ligand
BDBM23981
Substrate
n/a
Meas. Tech.
ChEBML_33548
EC50
>30000±n/a nM
Citation
 DeMarinis, RM; Bryan, WM; Shah, DH; Hieble, JP; Pendleton, RG Alpha-adrenergic agents. 1. Direct-acting alpha 1 agonists related to methoxamine. J Med Chem 24:1432-7 (1982) [PubMed]  Article 
Target
Name:
Alpha-1A adrenergic receptor
Synonyms:
ADA1A_HUMAN | ADRA1A | ADRA1C | Adrenergic alpha1A | Alpha 1A-adrenoceptor | Alpha 1A-adrenoreceptor | Alpha adrenergic receptor 1a | Alpha-1C adrenergic receptor | Alpha-adrenergic receptor 1c | Cerebral cortex alpha adrenergic receptor | adrenergic Alpha1 | adrenergic Alpha1C
Type:
Cell-surface receptors
Mol. Mass.:
51511.67
Organism:
Homo sapiens (Human)
Description:
P35348
Residue:
466
Sequence:
MVFLSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHALGYTLHPPSQAVEGQHKDMVRIPVGSRETFYRISKTDGVCEWKFFSSMPRGSARITVSKDQSSCTTARVRSKSFLQVCCCVGPSTPSLDKNHQVPTIKVHTISLSENGEEV
  
Inhibitor
Name:
BDBM23981
Synonyms:
(2S)-1,2,3,4-Tetrahydro-naphthalen-2-ylamine | 1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride | CHEMBL30294 | Tetrahydronaphthalen-2-amine, 3a
Type:
Small organic molecule
Emp. Form.:
C10H13N
Mol. Mass.:
147.2169
SMILES:
NC1CCc2ccccc2C1
Structure:
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