Reaction Details Report a problem with these data
Target
Thymidine kinase, cytosolic
Ligand
BDBM50404860
Substrate
n/a
Meas. Tech.
ChEMBL_208200 (CHEMBL878648)
Ki
3900±n/a nM
Citation
 Hampton, A; Chawla, RR; Kappler, F Species- or isozyme-specific enzyme inhibitors. 5. Differential effects of thymidine substituents on affinity for rat thymidine kinase isozymes. J Med Chem 25:644-9 (1982) [PubMed]  Article 
Target
Name:
Thymidine kinase, cytosolic
Synonyms:
KITH_RAT | Thymidine kinase | Tk-1 | Tk1
Type:
PROTEIN
Mol. Mass.:
13514.16
Organism:
Rattus norvegicus
Description:
ChEMBL_208200
Residue:
121
Sequence:
MSYINLPTVLPISPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTRYSNSFSTHDRNTMDALPACMLKDVAQEALGVAVIGIDEGQFFPDIVDFCETMANTGKTVIV
  
Inhibitor
Name:
BDBM50404860
Synonyms:
CHEMBL2111285
Type:
Small organic molecule
Emp. Form.:
C12H19BrN2O6
Mol. Mass.:
367.193
SMILES:
CCOC1N([C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)NC(=O)C1(C)Br |r|
Structure:
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