Reaction Details Report a problem with these data
Target
Thymidine kinase, cytosolic
Ligand
BDBM50000969
Substrate
n/a
Meas. Tech.
ChEBML_123825
Ki
36000±n/a nM
Citation
 Hampton, A; Chawla, RR; Kappler, F Species- or isozyme-specific enzyme inhibitors. 5. Differential effects of thymidine substituents on affinity for rat thymidine kinase isozymes. J Med Chem 25:644-9 (1982) [PubMed]  Article 
Target
Name:
Thymidine kinase, cytosolic
Synonyms:
KITH_RAT | Thymidine kinase | Tk-1 | Tk1
Type:
PROTEIN
Mol. Mass.:
13514.16
Organism:
Rattus norvegicus
Description:
ChEMBL_208200
Residue:
121
Sequence:
MSYINLPTVLPISPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTRYSNSFSTHDRNTMDALPACMLKDVAQEALGVAVIGIDEGQFFPDIVDFCETMANTGKTVIV
  
Inhibitor
Name:
BDBM50000969
Synonyms:
CHEMBL3143490
Type:
Small organic molecule
Emp. Form.:
C15H24N2O5
Mol. Mass.:
312.3615
SMILES:
CCCCCn1c(=O)c(C)cn([C@H]2C[C@H](O)[C@@H](CO)O2)c1=O |r|
Structure:
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