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Target
D(2) dopamine receptor
Ligand
BDBM50024708
Substrate
n/a
Meas. Tech.
ChEMBL_59310 (CHEMBL666963)
IC50
>100000±n/a nM
Citation
 Hall, AW; Taylor, RJ; Simmonds, SH; Strange, PG Synthesis of some [N-(2-haloalkyl)amino]tetralin derivatives as potential irreversible labels for bovine anterior pituitary D2 dopamine receptors. J Med Chem 30:1879-87 (1987) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DRD2 | DRD2_BOVIN | Dopamine D2 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50698.79
Organism:
BOVINE
Description:
P20288
Residue:
444
Sequence:
MDPLNLSWYDDDPESRNWSRPFNGSEGKADRPPYNYYAMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPMLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRANLKAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKTVNPKIAKIFEIQSMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50024708
Synonyms:
6-[(2-Bromo-ethyl)-propyl-amino]-5,6,7,8-tetrahydro-naphthalene-2,3-diol; hydrobromide | CHEMBL540272
Type:
Small organic molecule
Emp. Form.:
C15H22BrNO2
Mol. Mass.:
328.245
SMILES:
CCCN(CCBr)C1CCc2cc(O)c(O)cc2C1
Structure:
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