Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50367496
Substrate
n/a
Meas. Tech.
ChEMBL_28963 (CHEMBL640603)
IC50
11±n/a nM
Citation
 Kwatra, MM; Leung, E; Hosey, MM; Green, RD N6-phenyladenosines: pronounced effect of phenyl substituents on affinity for A2 adenosine receptors. J Med Chem 30:954-6 (1987) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_CHICK | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36337.19
Organism:
Chick
Description:
ADENOSINE A1 ADORA1 Chick::P49892
Residue:
324
Sequence:
MAQSVTAFQAAYISIEVLIALVSVPGNILVIWAVKMNQALRDATFCFIVSLAVADVAVGALVIPLAIIINIGPQTEFYSCLMMACPVLILTESSILALLAIAVDRYLRVKIPVRYKSVVTPRRAAVAIACCWIVSFLVGLTPMFGWNNLNKVLGTRDLNVSHSEFVIKCQFETVISMEYMVYFNFFVWVLPPLLLMLLIYLEVFNLIRTQLNKKVSSSSNDPQKYYGKELKIAKSLALVLFLFALSWLPLHILNCITLFCPSCKTPHILTYIAIFLTHGNSAMNPIVYAFRIKKFRTAFLQIWNQYFCCKTNKSSSSSTAETVN
  
Inhibitor
Name:
BDBM50367496
Synonyms:
CHEMBL609650
Type:
Small organic molecule
Emp. Form.:
C16H17N5O5
Mol. Mass.:
359.3367
SMILES:
OC[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(Nc3cccc(O)c3)ncnc12 |r|
Structure:
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