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Target
Thymidine kinase
Ligand
BDBM50013074
Substrate
n/a
Meas. Tech.
ChEBML_207840
EC50
50000±n/a nM
Citation
 Focher, F; Hildebrand, C; Freese, S; Ciarrocchi, G; Noonan, T; Sangalli, S; Brown, N; Spadari, S; Wright, G N2-phenyldeoxyguanosine: a novel selective inhibitor of herpes simplex thymidine kinase. J Med Chem 31:1496-500 (1988) [PubMed]  Article 
Target
Name:
Thymidine kinase
Synonyms:
KITH_HHV1S | TK | Thymidine kinase | UL23
Type:
PROTEIN
Mol. Mass.:
40883.42
Organism:
Human herpesvirus 1 (strain SC16) (HHV-1) (Human herpes simplex virus1)
Description:
ChEMBL_213
Residue:
376
Sequence:
MASYPGHQHASAFDQAARSRGHSNRRTALRPRRQQEATEVRPEQKMPTLLRVYIDGPHGMGKTTTTQLLVALGSRDDIVYVPEPMTYWRVLGASETIANIYTTQHRLDQGEISAGDAAVVMTSAQITMGMPYAVTDAVLAPHIGGEAGSSHAPPPALTLIFDRHPIAALLCYPAARYLMGSMTPQAVLAFVALIPPTLPGTNIVLGALPEDRHIDRLAKRQRPGERLDLAMLAAIRRVYGLLANTVRYLQGGGSWREDWGQLSGTAVPPQGAEPQSNAGPRPHIGDTLFTLFRAPELLAPNGDLYNVFAWALDVLAKRLRPMHVFILDYDQSPAGCRDALLQLTSGMIQTHVTTPGSIPTICDLARTFAREMGEAN
  
Inhibitor
Name:
BDBM50013074
Synonyms:
2-(4-Butyl-phenylamino)-1,9-dihydro-purin-6-one | 2-(4-Butyl-phenylamino)-1,9-dihydro-purin-6-one(BuPG) | CHEMBL16193
Type:
Small organic molecule
Emp. Form.:
C15H17N5O
Mol. Mass.:
283.3284
SMILES:
CCCCc1ccc(Nc2nc3nc[nH]c3c(=O)[nH]2)cc1
Structure:
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