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Target
Prostaglandin F2-alpha receptor
Ligand
BDBM50405735
Substrate
n/a
Meas. Tech.
ChEMBL_152620 (CHEMBL762787)
IC50
670±n/a nM
Citation
 Kawada, K; Dolence, EK; Morita, H; Kometani, T; Watt, DS; Balapure, A; Fitz, TA; Orlicky, DJ; Gerschenson, LE Prostaglandin photoaffinity probes: synthesis and biological activity of azide-substituted 16-phenoxy- and 17-phenyl-PGF2 alpha prostaglandins. J Med Chem 32:256-64 (1989) [PubMed]  Article 
Target
Name:
Prostaglandin F2-alpha receptor
Synonyms:
PF2R_BOVIN | PGF receptor | PGF2 alpha receptor | PTGFR | ProstaglandinF2Alpha | Prostanoid FP receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41044.75
Organism:
BOVINE
Description:
ProstaglandinF2Alpha PTGFR BOVINE::P37289
Residue:
362
Sequence:
MSTNSSIQPVSPESELLSNTTCQLEEDLSISFSIIFMTVGILSNSLAIAILMKAYQRFRQKYKSSFLLLASALVITDFFGHLINGTIAVFVYASDKDWIYFDKSNILCSIFGICMVFSGLCPLFLGSLMAIERCIGVTKPIFHSTKITTKHVKMMLSGVCFFAVFVALLPILGHRDYKIQASRTWCFYKTDEIKDWEDRFYLLLFAFLGLLALGISFVCNAITGISLLKVKFRSQQHRQGRSHHFEMVIQLLGIMCVSCICWSPFLVTMASIGMNIQDFKDSCERTLFTLRMATWNQILDPWVYILLRKAVLRNLYVCTRRCCGVHVISLHVWELSSIKDSLKVAAISDLPVTEKVTQQTST
  
Inhibitor
Name:
BDBM50405735
Synonyms:
CHEMBL2114230
Type:
Small organic molecule
Emp. Form.:
C25H36O5
Mol. Mass.:
416.5503
SMILES:
O[C@H](CCCCc1ccccc1)\C=C\C1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Structure:
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