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Target
Urokinase-type plasminogen activator
Ligand
BDBM50053620
Substrate
n/a
Meas. Tech.
ChEBML_213160
Ki
20606±n/a nM
Citation
 Yang, H; Henkin, J; Kim, KH; Greer, J Selective inhibition of urokinase by substituted phenylguanidines: quantitative structure-activity relationship analyses. J Med Chem 33:2956-61 (1990) [PubMed]  Article 
Target
Name:
Urokinase-type plasminogen activator
Synonyms:
3.4.21.73 | PLAU | U-plasminogen activator | UROK_HUMAN | Urokinase | Urokinase-type plasminogen activator (uPA) | Urokinase-type plasminogen activator chain B | Urokinase-type plasminogen activator long chain A | Urokinase-type plasminogen activator short chain A | Urokinase-type plasminogen activator/surface receptor | uPA
Type:
Enzyme
Mol. Mass.:
48528.62
Organism:
Homo sapiens (Human)
Description:
P00749
Residue:
431
Sequence:
MRALLARLLLCVLVVSDSKGSNELHQVPSNCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQHCEIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRRRPWCYVQVGLKLLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRFKIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTKEENGLAL
  
Inhibitor
Name:
BDBM50053620
Synonyms:
1-phenylguanidine | 1N-amino(immino)methylaniline | CHEMBL14047 | N-Phenyl-guanidine | N-phenylguanidine
Type:
Small organic molecule
Emp. Form.:
C7H9N3
Mol. Mass.:
135.1665
SMILES:
[#7]\[#6](-[#7])=[#7]\c1ccccc1
Structure:
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