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Target
Platelet-activating factor receptor
Ligand
BDBM50014010
Substrate
n/a
Meas. Tech.
ChEBML_155157
Ki
2092±n/a nM
Citation
 Sunkel, CE; de Casa-Juana, MF; Santos, L; Gómez, MM; Villarroya, M; González-Morales, MA; Priego, JG; Ortega, MP 4-Alkyl-1,4-dihydropyridines derivatives as specific PAF-acether antagonists. J Med Chem 33:3205-10 (1991) [PubMed]  Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Protein
Mol. Mass.:
39005.63
Organism:
Cavia porcellus
Description:
n/a
Residue:
342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
  
Inhibitor
Name:
BDBM50014010
Synonyms:
2,4,6-Trimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-phenylsulfanyl-ethyl) ester 5-(tetrahydro-furan-2-ylmethyl) ester | CHEMBL326215
Type:
Small organic molecule
Emp. Form.:
C23H29NO5S
Mol. Mass.:
431.545
SMILES:
CC1C(C(=O)OCC2CCCO2)C(C)=NC(C)=C1C(=O)OCCSc1ccccc1 |c:14,17|
Structure:
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