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Target
Kappa-type opioid receptor
Ligand
BDBM50013857
Substrate
n/a
Meas. Tech.
ChEBML_146790
Ki
1±n/a nM
Citation
 Galzi, JL; Mejean, A; Ilien, B; Mollereau, C; Meunier, JC; Goeldner, M; Hirth, C Photoactivatable opiate derivatives as irreversible probes of the mu-opioid receptor. J Med Chem 33:2456-64 (1990) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42744.99
Organism:
Cavia porcellus (domestic guinea pig)
Description:
P41144
Residue:
380
Sequence:
MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRVRNTVQDPAYMRNVDGVNKPV
  
Inhibitor
Name:
BDBM50013857
Synonyms:
14-[4-diazo(methyl)anilino]-4-cyclopropylmethyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-triene-10,17-diol salt (naltrexonediazonium) | CHEMBL311995
Type:
Small organic molecule
Emp. Form.:
C27H31N4O3
Mol. Mass.:
459.5595
SMILES:
CN(C1CCC2(O)C3Cc4ccc(O)c5OC1C2(CCN3CC1CC1)c45)c1ccc(cc1)[N+]#N |TLB:14:25:5:20.18.19,10:9:5:20.18.19,THB:4:5:25.9.8:20.18.19|
Structure:
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