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Target
Delta-type opioid receptor
Ligand
BDBM50013855
Substrate
n/a
Meas. Tech.
ChEBML_145688
Ki
100±n/a nM
Citation
 Galzi, JL; Mejean, A; Ilien, B; Mollereau, C; Meunier, JC; Goeldner, M; Hirth, C Photoactivatable opiate derivatives as irreversible probes of the mu-opioid receptor. J Med Chem 33:2456-64 (1990) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
Cytochrome P450 3A4 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor | Delta-type opioid receptor (DOR) | OPIATE Delta | OPRD_RAT | Opiate Delta 1 | Opioid receptor | Opioid receptor A | Opioid receptors; mu & delta | Oprd1 | Ror-a | Voltage-gated potassium channel
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40465.04
Organism:
Rattus norvegicus (rat)
Description:
Competition binding assays were using CHO-K1 cell membranes expressing the opioid receptor.
Residue:
372
Sequence:
MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50013855
Synonyms:
1-(4-Azido-phenyl)-8-[1-(4-chloro-phenyl)-ethyl]-1,3,8-triaza-spiro[4.5]decan-4-one | CHEMBL312046
Type:
Small organic molecule
Emp. Form.:
C21H23ClN6O
Mol. Mass.:
410.9
SMILES:
CC(N1CCC2(CC1)N(CNC2=O)c1ccc(cc1)N=[N+]=[N-])c1ccc(Cl)cc1
Structure:
Search PDB for entries with ligand similarity: