Reaction Details Report a problem with these data
Target
S-adenosylmethionine decarboxylase proenzyme
Ligand
BDBM50368644
Substrate
n/a
Meas. Tech.
ChEBML_197688
IC50
5±n/a nM
Citation
 Stanek, J; Caravatti, G; Frei, J; Furet, P; Mett, H; Schneider, P; Regenass, U 4-Amidinoindan-1-one 2'-amidinohydrazone: a new potent and selective inhibitor of S-Adenosylmethionine decarboxylase. J Med Chem 36:2168-71 (1993) [PubMed]  Article 
Target
Name:
S-adenosylmethionine decarboxylase proenzyme
Synonyms:
Amd1 | DCAM_RAT | S-adenosylmethionine decarboxylase 1
Type:
PROTEIN
Mol. Mass.:
38134.93
Organism:
Rattus norvegicus
Description:
ChEMBL_197052
Residue:
333
Sequence:
MEAAHFFEGTEKLLEVWFSRQQSDASQGSGDLRTIPRSEWDVLLKDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDLPESRVINQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATLFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLSSPQKIDGFKRLDCQSAMFNDYNFVFTSFAKKQQQQS
  
Inhibitor
Name:
BDBM50368644
Synonyms:
CHEMBL1202793 | Sardomozide chloride
Type:
Small organic molecule
Emp. Form.:
C11H14N6
Mol. Mass.:
230.2691
SMILES:
NC(=N)NN=C1CCc2c1cccc2C(N)=N |w:4.3|
Structure:
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