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Target
D(1A) dopamine receptor
Ligand
BDBM50040281
Substrate
n/a
Meas. Tech.
ChEBML_58175
IC50
>10000±n/a nM
Citation
 Wyrick, SD; Booth, RG; Myers, AM; Owens, CE; Kula, NS; Baldessarini, RJ; McPhail, AT; Mailman, RB Synthesis and pharmacological evaluation of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as ligands for a novel receptor with sigma-like neuromodulatory activity. J Med Chem 36:2542-51 (1993) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49429.75
Organism:
RAT
Description:
P18901
Residue:
446
Sequence:
MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDTEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST
  
Inhibitor
Name:
BDBM50040281
Synonyms:
CHEMBL105645 | CHEMBL543134 | cis-7-Dimethylamino-5-phenyl-5,6,7,8-tetrahydro-naphthalene-2,3-diol; hydrobromide | trans-7-Dimethylamino-5-phenyl-5,6,7,8-tetrahydro-naphthalene-2,3-diol; hydrobromide
Type:
Small organic molecule
Emp. Form.:
C18H21NO2
Mol. Mass.:
283.3648
SMILES:
CN(C)C1CC(c2ccccc2)c2cc(O)c(O)cc2C1
Structure:
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