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Target
D(1A) dopamine receptor
Ligand
BDBM50040287
Substrate
n/a
Meas. Tech.
ChEBML_58175
IC50
3100±n/a nM
Citation
 Wyrick, SD; Booth, RG; Myers, AM; Owens, CE; Kula, NS; Baldessarini, RJ; McPhail, AT; Mailman, RB Synthesis and pharmacological evaluation of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as ligands for a novel receptor with sigma-like neuromodulatory activity. J Med Chem 36:2542-51 (1993) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49429.75
Organism:
RAT
Description:
P18901
Residue:
446
Sequence:
MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDTEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST
  
Inhibitor
Name:
BDBM50040287
Synonyms:
(1R,3S)Dimethyl-(2-methyl-4-phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine; hydrochloride | (1S, 3R) Dimethyl-(2-methyl-4-phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine; hydrochloride | CHEMBL542167 | Dimethyl-(4-phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine; hydrochloride
Type:
Small organic molecule
Emp. Form.:
C19H23N
Mol. Mass.:
265.3926
SMILES:
CN(C)[C@]1(C)C[C@@H](c2ccccc2)c2ccccc2C1
Structure:
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