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Target
Cathepsin B
Ligand
BDBM50046899
Substrate
n/a
Meas. Tech.
ChEMBL_47253 (CHEMBL656659)
IC50
100±n/a nM
Citation
 McConnell, RM; York, JL; Frizzell, D; Ezell, C Inhibition studies of some serine and thiol proteinases by new leupeptin analogues. J Med Chem 36:1084-9 (1993) [PubMed]  Article 
Target
Name:
Cathepsin B
Synonyms:
BCSB | CATB_BOVIN | CTSB | Cathepsin B precursor | Cathepsin B1
Type:
Enzyme
Mol. Mass.:
36657.87
Organism:
Bos taurus (bovine)
Description:
Bovine spleen CB was purchased from Sigma Co. (USA).
Residue:
335
Sequence:
MWRLLATLSCLLVLTSARSSLYFPPLSDELVNFVNKQNTTWKAGHNFYNVDLSYVKKLCGAILGGPKLPQRDAFAADVVLPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVNVEVSAEDMLTCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVSGEIMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDNGFFKILRGQDHCGIESEIVAGMPCTHQY
  
Inhibitor
Name:
BDBM50046899
Synonyms:
2-Acetylamino-4-methyl-pentanoic acid [1-(5-amino-1-formyl-pentylcarbamoyl)-2-phenyl-ethyl]-amide | CHEMBL2373042
Type:
Small organic molecule
Emp. Form.:
C23H36N4O4
Mol. Mass.:
432.5563
SMILES:
CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C=O |r|
Structure:
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