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Target
D(2) dopamine receptor
Ligand
BDBM50039771
Substrate
n/a
Meas. Tech.
ChEMBL_63048 (CHEMBL679938)
Ki
>1500±n/a nM
Citation
 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikström, H Substituted (S)-phenylpiperidines and rigid congeners as preferential dopamine autoreceptor antagonists: synthesis and structure-activity relationships. J Med Chem 37:2735-53 (1994) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50039771
Synonyms:
3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-6-carboxylic acid amide | CHEMBL96726
Type:
Small organic molecule
Emp. Form.:
C16H20N2O
Mol. Mass.:
256.3428
SMILES:
NC(=O)c1cccc2C3CCN(CC=C)C3CCc12
Structure:
Search PDB for entries with ligand similarity: