Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50034904
Substrate
n/a
Meas. Tech.
ChEMBL_30616 (CHEMBL642023)
Ki
3470±n/a nM
Citation
 Jacobson, KA; Siddiqi, SM; Olah, ME; Ji, XD; Melman, N; Bellamkonda, K; Meshulam, Y; Stiles, GL; Kim, HO Structure-activity relationships of 9-alkyladenine and ribose-modified adenosine derivatives at rat A3 adenosine receptors. J Med Chem 38:1720-35 (1995) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
AA3R_RAT | Adenosine A3 receptor | Adenosine receptor A2a and A3 | Adora3
Type:
PROTEIN
Mol. Mass.:
36643.73
Organism:
Rattus norvegicus
Description:
ChEMBL_479910
Residue:
320
Sequence:
MKANNTTTSALWLQITYITMEAAIGLCAVVGNMLVIWVVKLNRTLRTTTFYFIVSLALADIAVGVLVIPLAIAVSLEVQMHFYACLFMSCVLLVFTHASIMSLLAIAVDRYLRVKLTVRYRTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKVTLELSQNSSTLSCHFRSVVGLDYMVFFSFITWILIPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFLFALCWLPLSIINFVSYFNVKIPEIAMCLGILLSHANSMMNPIVYACKIKKFKETYFVILRACRLCQTSDSLDSNLEQTTE
  
Inhibitor
Name:
BDBM50034904
Synonyms:
CHEMBL49758 | N-[2-Chloro-9-(tetrahydro-furan-2-yl)-9H-purin-6-yl]-3-iodo-benzamide
Type:
Small organic molecule
Emp. Form.:
C16H13ClIN5O2
Mol. Mass.:
469.664
SMILES:
Clc1nc(NC(=O)c2cccc(I)c2)c2ncn(C3CCCO3)c2n1
Structure:
Search PDB for entries with ligand similarity: