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Target
D(2) dopamine receptor
Ligand
BDBM50035383
Substrate
n/a
Meas. Tech.
ChEMBL_59156 (CHEMBL671187)
Ki
74±n/a nM
Citation
 Thurkauf, A; Hutchison, A; Peterson, J; Cornfield, L; Meade, R; Huston, K; Harris, K; Ross, PC; Gerber, K; Ramabhadran, TV 2-Phenyl-4-(aminomethyl)imidazoles as potential antipsychotic agents. Synthesis and dopamine D2 receptor binding. J Med Chem 38:2251-5 (1995) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DRD2 | DRD2_CHLAE | Dopamine D2 receptor
Type:
PROTEIN
Mol. Mass.:
50619.11
Organism:
Cercopithecus aethiops
Description:
ChEMBL_59156
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSKIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRSHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKNHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50035383
Synonyms:
Benzyl-[2-(2-methoxy-phenyl)-3H-imidazol-4-ylmethyl]-methyl-amine; dihydrochloride | CHEMBL555067
Type:
Small organic molecule
Emp. Form.:
C19H21N3O
Mol. Mass.:
307.3895
SMILES:
COc1ccccc1-c1ncc(CN(C)Cc2ccccc2)[nH]1
Structure:
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