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Target
Metabotropic glutamate receptor 8
Ligand
BDBM66976
Substrate
n/a
Meas. Tech.
ChEMBL_104621 (CHEMBL715569)
EC50
>100000±n/a nM
Citation
 Knöpfel, T; Kuhn, R; Allgeier, H Metabotropic glutamate receptors: novel targets for drug development. J Med Chem 38:1417-26 (1995) [PubMed]  Article 
Target
Name:
Metabotropic glutamate receptor 8
Synonyms:
GRM8_MOUSE | Gprc1h | Grm8 | Mglur8
Type:
PROTEIN
Mol. Mass.:
101846.09
Organism:
Mus musculus
Description:
ChEMBL_12951
Residue:
908
Sequence:
MVCEGKRSTSCPCFFLLTAKFYWILTMMQRTHSQEYAHSIRLDGDIILGGLFPVHAKGERGVPCGDLKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKELCPGYIGLCPRMVTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQINNKSTEYKIIGHWTNQLHLKVEDMQWANREHTHPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNINRTGCQRIPIIKLEWHSPWAVVPVFIAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRIFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPHTIIDYGEQRTLDPENARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNTSSTKTTYISYSNHSI
  
Inhibitor
Name:
BDBM66976
Synonyms:
(1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;hydrate | (1S,3R)-1-azanylcyclopentane-1,3-dicarboxylic acid;hydrate | CHEMBL34453 | MLS002153209 | SMR001230688 | cid_16218853 | trans-( )-ACPD monohydrate
Type:
Small organic molecule
Emp. Form.:
C7H11NO4
Mol. Mass.:
173.1665
SMILES:
N[C@]1(CC[C@H](C1)C(O)=O)C(O)=O
Structure:
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