Reaction Details Report a problem with these data
Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM500
Substrate
n/a
Meas. Tech.
ChEMBL_159456 (CHEMBL766801)
IC50
21000±n/a nM
Citation
 Mazumder, A; Wang, S; Neamati, N; Nicklaus, M; Sunder, S; Chen, J; Milne, GW; Rice, WG; Burke, TR; Pommier, Y Antiretroviral agents as inhibitors of both human immunodeficiency virus type 1 integrase and protease. J Med Chem 39:2472-81 (1996) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM500
Synonyms:
4-hydroxy-3-[(4-hydroxy-2-oxo-3,4-dihydro-2H-1-benzopyran-3-yl)sulfanyl]-2H-chromen-2-one | CHEMBL303093 | Cancer Chemotherapy National Service Center (CCNSC) compound 41234 | NSC 41234
Type:
Small organic molecule
Emp. Form.:
C18H12O6S
Mol. Mass.:
356.349
SMILES:
OC1C(Sc2c(O)c3ccccc3oc2=O)C(=O)Oc2ccccc12
Structure:
Search PDB for entries with ligand similarity: