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Target
Melanocortin receptor 3
Ligand
BDBM50058963
Substrate
n/a
Meas. Tech.
ChEMBL_106014 (CHEMBL716370)
IC50
>10000±n/a nM
Citation
 Haskell-Luevano, C; Hendrata, S; North, C; Sawyer, TK; Hadley, ME; Hruby, VJ; Dickinson, C; Gantz, I Discovery of prototype peptidomimetic agonists at the human melanocortin receptors MC1R and MC4R. J Med Chem 40:2133-9 (1997) [PubMed]  Article 
Target
Name:
Melanocortin receptor 3
Synonyms:
MC3-R | MC3R | MC3R_HUMAN | Melanocortin MC3 | Melanocortin receptor (M3 and M4)
Type:
Enzyme
Mol. Mass.:
36044.86
Organism:
Homo sapiens (Human)
Description:
P41968
Residue:
323
Sequence:
MNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGCNGMNLG
  
Inhibitor
Name:
BDBM50058963
Synonyms:
Ac-His-DPhe-Arg-DTrp-NH2 | Ac-His-DPhe-DArg-DTrp-NH2 | CHEMBL433296
Type:
Small organic molecule
Emp. Form.:
C34H43N11O5
Mol. Mass.:
685.7759
SMILES:
CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(N)=O
Structure:
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