Reaction Details Report a problem with these data
Target
Somatostatin receptor type 3
Ligand
BDBM50059088
Substrate
n/a
Meas. Tech.
ChEMBL_200510 (CHEMBL803854)
IC50
>1000±n/a nM
Citation
 Osapay, G; Prokai, L; Kim, HS; Medzihradszky, KF; Coy, DH; Liapakis, G; Reisine, T; Melacini, G; Zhu, Q; Wang, SH; Mattern, RH; Goodman, M Lanthionine-somatostatin analogs: synthesis, characterization, biological activity, and enzymatic stability studies. J Med Chem 40:2241-51 (1997) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 3
Synonyms:
SOMATOSTATIN SST3 | SS3R | SSR-28 | SSR3_MOUSE | Smstr3 | Somatostatin receptor | Somatostatin receptor 3 | Somatostatin receptor type 3 | Sstr3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
47225.49
Organism:
MOUSE
Description:
SOMATOSTATIN SST3 SSTR3 MOUSE::P30935
Residue:
428
Sequence:
MATVTYPSSEPTTLDPGNASSTWPLDTTLGNTSAGASLTGLAVSGILISLVYLVVCVVGLLGNSLVIYVVLRHTSSPSVTSVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRTAFIIYTAALGFFGPLLVICLCYLLIVVKVRSTTRRVRAPSCQWVQAPACQRRRRSERRVTRMVVAVVALFVLCWMPFYLLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRILLRPSRRIRSQEPGSGPPEKTEEEEDEEEEERREEEERRMQRGQEMNGRLSQIAQAGTSGQQPRPCTGTAKEQQLLPQEATAGDKASTLSHL
  
Inhibitor
Name:
BDBM50059088
Synonyms:
(3S,6R,9S,12R,15S,18R)-18-Amino-9-(4-amino-butyl)-15-benzyl-6-((R)-1-hydroxy-ethyl)-12-(1H-indol-3-ylmethyl)-5,8,11,14,17-pentaoxo-1-thia-4,7,10,13,16-pentaaza-cyclononadecane-3-carboxylic acid | CHEMBL306702
Type:
Small organic molecule
Emp. Form.:
C36H48N8O8S
Mol. Mass.:
752.88
SMILES:
C[C@@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSC[C@@H](NC1=O)C(O)=O
Structure:
Search PDB for entries with ligand similarity: