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Target
Mu-type opioid receptor
Ligand
BDBM50039024
Substrate
n/a
Meas. Tech.
ChEMBL_146976 (CHEMBL757515)
IC50
1517±n/a nM
Citation
 Calderon, SN; Rice, KC; Rothman, RB; Porreca, F; Flippen-Anderson, JL; Kayakiri, H; Xu, H; Becketts, K; Smith, LE; Bilsky, EJ; Davis, P; Horvath, R Probes for narcotic receptor mediated phenomena. 23. Synthesis, opioid receptor binding, and bioassay of the highly selective delta agonist (+)-4-[(alpha R)-alpha-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]- N,N-diethylbenzamide (SNC 80) and related novel nonpeptide delta opioid r J Med Chem 40:695-704 (1997) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50039024
Synonyms:
4-[(S)-((2R,5S)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide | CHEMBL65648 | cid_16219954
Type:
Small organic molecule
Emp. Form.:
C28H39N3O2
Mol. Mass.:
449.6282
SMILES:
CCN(CC)C(=O)c1ccc(cc1)[C@H](N1C[C@H](C)N(CC=C)C[C@H]1C)c1cccc(OC)c1
Structure:
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