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Target
Somatostatin receptor type 3
Ligand
BDBM50063817
Substrate
n/a
Meas. Tech.
ChEMBL_200502 (CHEMBL803847)
IC50
1756±n/a nM
Citation
 Hocart, SJ; Jain, R; Murphy, WA; Taylor, JE; Morgan, B; Coy, DH Potent antagonists of somatostatin: synthesis and biology. J Med Chem 41:1146-54 (1998) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 3
Synonyms:
SOMATOSTATIN SST3 | SS-3-R | SS3-R | SS3R | SSR-28 | SSR3_HUMAN | SSTR3 | Somatostatin receptor type 3 (SSTR3)
Type:
Protein
Mol. Mass.:
45855.97
Organism:
Homo sapiens (Human)
Description:
P32745
Residue:
418
Sequence:
MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL
  
Inhibitor
Name:
BDBM50063817
Synonyms:
CHEMBL429371 | H-Dip-cyclo[DCys-His-DTrp-Lys-Val-Cys]-Dip-NH2
Type:
Small organic molecule
Emp. Form.:
C64H75N13O8S2
Mol. Mass.:
1218.493
SMILES:
CC(C)[C@@H]1NC(=O)[C@@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2cnc[nH]2)NC(=O)[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1cccc(c1)-c1ccccc1)C(N)=O)NC(=O)[C@@H](N)Cc1cccc(c1)-c1ccccc1
Structure:
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