Reaction Details Report a problem with these data
Target
S-adenosylmethionine decarboxylase proenzyme
Ligand
BDBM50369827
Substrate
n/a
Meas. Tech.
ChEMBL_197498 (CHEMBL805132)
Ki
560±n/a nM
Citation
 Casero, RA; Woster, PM Terminally alkylated polyamine analogues as chemotherapeutic agents. J Med Chem 44:1-26 (2001) [PubMed]  Article 
Target
Name:
S-adenosylmethionine decarboxylase proenzyme
Synonyms:
Amd1 | DCAM_RAT | S-adenosylmethionine decarboxylase 1
Type:
PROTEIN
Mol. Mass.:
38134.93
Organism:
Rattus norvegicus
Description:
ChEMBL_197052
Residue:
333
Sequence:
MEAAHFFEGTEKLLEVWFSRQQSDASQGSGDLRTIPRSEWDVLLKDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDLPESRVINQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATLFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLSSPQKIDGFKRLDCQSAMFNDYNFVFTSFAKKQQQQS
  
Inhibitor
Name:
BDBM50369827
Synonyms:
CHEMBL611536
Type:
Small organic molecule
Emp. Form.:
C13H19N7O3
Mol. Mass.:
321.3351
SMILES:
NCCC=NC[C@@H]1OC([C@@H](O)[C@H]1O)n1cnc2c(N)ncnc12 |r,w:3.2|
Structure:
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