Target
Transporter
Ligand
BDBM50095137
Substrate
n/a
Meas. Tech.
ChEMBL_142971 (CHEMBL752041)
Ki
393±n/a nM
Citation
 Tamiz, APBandyopadhyay, BCZhang, JFlippen-Anderson, JLZhang, MWang, CZJohnson, KMTella, SKozikowski, AP Pharmacological and behavioral analysis of the effects of some bivalent ligand-based monoamine reuptake inhibitors. J Med Chem 44:1615-22 (2001) [PubMed]  Article 
Target
Name:
Transporter
Synonyms:
Monoamine transporters; Norepininephrine & dopamine | Norepinephrine Monoamine transporters
Type:
PROTEIN
Mol. Mass.:
66787.87
Organism:
Rattus norvegicus
Description:
ChEMBL_1463061
Residue:
597
Sequence:
MVTRTRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQFNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLNLPWTNCGHAWNSPNCTDPKLLNASVLGDHTKYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVIVVLYVSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTINCVTSFISGFAIFSILGYMAHEHKVKIEDVATEGAGLVFVLYPEAISTLSGSTFWAVLFFLMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTCAVTLGTFLLAMFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYVYPPWANWVGWGIALSSMILVPAYVIYKFFSIRGSLWERVAYGITPENEHHLLALEIELSSLQSFVITSCPIDPLLSSFLFISCQKTLVFKKSGPAPLI
  
Inhibitor
Name:
BDBM50095137
Synonyms:
(3S,4R)-4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxylic acid (5-{[(3S,4R)-4-(4-chloro-phenyl)-1-methyl-piperidine-3-carbonyl]-amino}-pentyl)-amide | 3N-{5-[4-(4-chlorophenyl)-1-methyl-(3S,4R)-hexahydro-3-pyridinylcarboxamido]pentyl}-4-(4-chlorophenyl)-1-methyl-(3S,4R)-hexahydro-3-pyridinecarboxamide | CHEMBL41995
Type:
Small organic molecule
Emp. Form.:
C31H42Cl2N4O2
Mol. Mass.:
573.597
SMILES:
CN1CC[C@H]([C@@H](C1)C(=O)NCCCCCNC(=O)[C@@H]1CN(C)CC[C@H]1c1ccc(Cl)cc1)c1ccc(Cl)cc1
Structure:
Search PDB for entries with ligand similarity: