Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50369084
Substrate
n/a
Meas. Tech.
ChEMBL_29318 (CHEMBL642306)
Ki
90.5±n/a nM
Citation
 Rieger, JM; Brown, ML; Sullivan, GW; Linden, J; Macdonald, TL Design, synthesis, and evaluation of novel A2A adenosine receptor agonists. J Med Chem 44:531-9 (2001) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50369084
Synonyms:
CHEMBL604440
Type:
Small organic molecule
Emp. Form.:
C19H25N7O5
Mol. Mass.:
431.4457
SMILES:
CCNC(=O)[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(N)nc(nc12)C#CCN1CCOCC1 |r|
Structure:
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