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Target
Macrophage migration inhibitory factor
Ligand
BDBM50095998
Substrate
n/a
Meas. Tech.
ChEMBL_103898 (CHEMBL711480)
Kd
2500000±n/a nM
Citation
 Orita, M; Yamamoto, S; Katayama, N; Aoki, M; Takayama, K; Yamagiwa, Y; Seki, N; Suzuki, H; Kurihara, H; Sakashita, H; Takeuchi, M; Fujita, S; Yamada, T; Tanaka, A Coumarin and chromen-4-one analogues as tautomerase inhibitors of macrophage migration inhibitory factor: discovery and X-ray crystallography. J Med Chem 44:540-7 (2001) [PubMed]  Article 
Target
Name:
Macrophage migration inhibitory factor
Synonyms:
GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase
Type:
Enzyme
Mol. Mass.:
12478.18
Organism:
Homo sapiens (Human)
Description:
P14174
Residue:
115
Sequence:
MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
  
Inhibitor
Name:
BDBM50095998
Synonyms:
CHEMBL345292 | Hexylglutathione | L-gamma-glutamyl-S-hexyl-L-cysteinylglycine | S-hexylglutathione
Type:
Small organic molecule
Emp. Form.:
C16H29N3O6S
Mol. Mass.:
391.483
SMILES:
CCCCCCSC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O
Structure:
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