Reaction Details Report a problem with these data
Target
P2X purinoceptor 1
Ligand
BDBM50118215
Substrate
n/a
Meas. Tech.
ChEMBL_149730 (CHEMBL759513)
EC50
1.5±n/a nM
Citation
 Jacobson, KA; Jarvis, MF; Williams, M Purine and pyrimidine (P2) receptors as drug targets. J Med Chem 45:4057-93 (2002) [PubMed]  Article 
Target
Name:
P2X purinoceptor 1
Synonyms:
ATP receptor | P2RX1_RAT | P2X1 | P2rx1 | Purinergic receptor | Purinergic, P2X1 | RP-2 protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44969.95
Organism:
RAT
Description:
Purinergic, P2X1 0 RAT::P47824
Residue:
399
Sequence:
MARRLQDELSAFFFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFVYEKGYQTSSDLISSVSVKLKGLAVTQLQGLGPQVWDVADYVFPAHGDSSFVVMTNFIVTPQQTQGHCAENPEGGICQDDSGCTPGKAERKAQGIRTGNCVPFNGTVKTCEIFGWCPVEVDDKIPSPALLREAENFTLFIKNSISFPRFKVNRRNLVEEVNGTYMKKCLYHKIQHPLCPVFNLGYVVRESGQDFRSLAEKGGVVGITIDWKCDLDWHVRHCKPIYQFHGLYGEKNLSPGFNFRFARHFVQNGTNRRHLFKVFGIHFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLHILPKRHYYKQKKFKYAEDMGPGEGEHDPVATSSTLGLQENMRTS
  
Inhibitor
Name:
BDBM50118215
Synonyms:
CHEMBL1628528 | Ip5I
Type:
Small organic molecule
Emp. Form.:
C20H27N8O24P5
Mol. Mass.:
918.3364
SMILES:
O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c2nc[nH]c3=O)O[C@H]([C@@H]1O)n1cnc2c1nc[nH]c2=O |r|
Structure:
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