Reaction Details Report a problem with these data
Target
Fibroblast growth factor 1
Ligand
BDBM50409925
Substrate
n/a
Meas. Tech.
ChEMBL_70628 (CHEMBL678684)
Kd
540±n/a nM
Citation
 Bytheway, I; Cochran, S Validation of molecular docking calculations involving FGF-1 and FGF-2. J Med Chem 47:1683-93 (2004) [PubMed]  Article 
Target
Name:
Fibroblast growth factor 1
Synonyms:
Acidic fibroblast growth factor | Beta-endothelial cell growth factor | ECGF-beta | FGF1 | FGF1_HUMAN | FGFA | Fibroblast growth factor 1 (FGF-1) | HBGF-1 | Heparin-binding growth factor 1 | aFGF
Type:
Protein
Mol. Mass.:
17461.01
Organism:
Homo sapiens (Human)
Description:
P05230
Residue:
155
Sequence:
MAEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD
  
Inhibitor
Name:
BDBM50409925
Synonyms:
CHEMBL2093120
Type:
Small organic molecule
Emp. Form.:
C12H22O35S8
Mol. Mass.:
982.802
SMILES:
OS(=O)(=O)OC[C@@H]1OC(OS(O)(=O)=O)[C@@H](OS(O)(=O)=O)[C@@H](OS(O)(=O)=O)[C@@H]1O[C@H]1O[C@@H](COS(O)(=O)=O)[C@H](OS(O)(=O)=O)[C@@H](OS(O)(=O)=O)[C@@H]1OS(O)(=O)=O |r,w:8.8|
Structure:
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