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Target
Cytosolic beta-glucosidase
Ligand
BDBM50118923
Substrate
n/a
Meas. Tech.
ChEMBL_305521 (CHEMBL827658)
IC50
<1000000±n/a nM
Citation
 Ogawa, S; Funayama, S; Okazaki, K; Ishizuka, F; Sakata, Y; Doi, F Synthesis of 5a-carba-hexopyranoses and hexopyranosylamines, as well as 5a,5a'-dicarbadisaccharides, from 3,8-dioxatricyclo[4.2.1.0(2,4)]nonan-9-ol: glycosidase inhibitory activity of N-substituted 5a-carba-beta-gluco- and beta-galactopyranosylamines, and derivatives thereof. Bioorg Med Chem Lett 14:5183-8 (2004) [PubMed]  Article 
Target
Name:
Cytosolic beta-glucosidase
Synonyms:
Beta-glucosidase cytosolic | CBG | CBGL1 | GBA3 | GBA3_HUMAN
Type:
PROTEIN
Mol. Mass.:
53687.94
Organism:
Homo sapiens (Human)
Description:
ChEMBL_820008
Residue:
469
Sequence:
MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL
  
Inhibitor
Name:
BDBM50118923
Synonyms:
(1S,2S,3R)-4-Methyl-6-octylamino-cyclohexane-1,2,3-triol | 4-Methyl-6-octylamino-cyclohexane-1,2,3-triol | CHEMBL314757
Type:
Small organic molecule
Emp. Form.:
C15H31NO3
Mol. Mass.:
273.4115
SMILES:
CCCCCCCCNC1CC(C)C(O)C(O)C1O
Structure:
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