Reaction Details Report a problem with these data
Target
Putative alpha-glucosidase
Ligand
BDBM50156354
Substrate
n/a
Meas. Tech.
ChEMBL_304940 (CHEMBL826969)
IC50
700±n/a nM
Citation
 Godin, G; Compain, P; Martin, OR; Ikeda, K; Yu, L; Asano, N Alpha-1-C-alkyl-1-deoxynojirimycin derivatives as potent and selective inhibitors of intestinal isomaltase: remarkable effect of the alkyl chain length on glycosidase inhibitory profile. Bioorg Med Chem Lett 14:5991-5 (2004) [PubMed]  Article 
Target
Name:
Putative alpha-glucosidase
Synonyms:
Alpha-glucosidase
Type:
PROTEIN
Mol. Mass.:
102549.55
Organism:
Oryza sativa subsp. japonica
Description:
ChEMBL_304920
Residue:
929
Sequence:
MLASLSSSSRAAISCIPLCLLFLTLASSNGVFAAAPPKVGSGYKLVSLVEHPEGGALVGYLQVKQRTSTYGPDIPLLRLYVKHETKDRIRVQITDADKPRWEVPYNLLQREPAPPVTGGRITGVPFAAGEYPGEELVFTYGRDPFWFAVHRKSSREALFNTSCGALVFKDQYIEASTSLPRDAALYGLGENTQPGGIRLRPNDPYTIYTTDISAINLNTDLYGSHPVYVDLRSRGGHGVAHAVLLLNSNGMDVFYRGTSLTYKVIGGLLDFYLFSGPTPLAVVDQYTSMIGRPAPMPYWAFGFHQCRWGYKNLSVVEGVVEGYRNAQIPLDVIWNDDDHMDAAKDFTLDPVNYPRPKLLEFLDKIHAQGMKYIVLIDPGIAVNNTYGVYQRGMQGDVFIKLDGKPYLAQVWPGPVYFPDFLNPNGVSWWIDEVRRFHDLVPVDGLWIDMNEASNFCTGKCEIPTTHLCPLPNTTTPWVCCLDCKNLTNTRWDEPPYKINASGQTARLGFNTIATSATHYNGILEYNAHSLYGFSQAIATHQALQGLQGKRPFILTRSTFVGSGAYAAHWTGDNKGTWENLRYSISTMLNFGIFGMPMVGADICGFYPQPTEELCNRWIELGAFYPFSRDHANFASPRQELYVWESVAKSARNALGMRYRLLPYLYTLNYQAHLTGAPVARPVFFSFPDFTPCYGLSTQYLLGASVMVSPVLEQGATSVSAMFPPGSWYNLFDTTKVVVSRGEGAVKLDAPLNEINVHVFQNTILPMQRGGTISKEARATPFTLVVAFPFGATEAEAEGAVYVDDDERPEMVLAEGQATYVRFYATVRGKAVTVRSEVELGSYSLQKGLLIEKLSVLGLEGTGRDLAVHVDGANATAIATSRPYFAGAEAELHGHRDVEGHKKSVMVEVGGLALPLGKSFTMTWNMQIEA
  
Inhibitor
Name:
BDBM50156354
Synonyms:
1-Hexyl-2-hydroxymethyl-piperidine-3,4,5-triol | CHEMBL186150
Type:
Small organic molecule
Emp. Form.:
C12H25NO4
Mol. Mass.:
247.3312
SMILES:
CCCCCCN1CC(O)C(O)C(O)C1CO
Structure:
Search PDB for entries with ligand similarity: