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Target
Cytosolic beta-glucosidase
Ligand
BDBM18351
Substrate
n/a
Meas. Tech.
ChEMBL_304934 (CHEMBL826964)
IC50
240000±n/a nM
Citation
 Kato, A; Kato, N; Kano, E; Adachi, I; Ikeda, K; Yu, L; Okamoto, T; Banba, Y; Ouchi, H; Takahata, H; Asano, N Biological properties of D- and L-1-deoxyazasugars. J Med Chem 48:2036-44 (2005) [PubMed]  Article 
Target
Name:
Cytosolic beta-glucosidase
Synonyms:
Beta-glucosidase cytosolic | CBG | CBGL1 | GBA3 | GBA3_HUMAN
Type:
PROTEIN
Mol. Mass.:
53687.94
Organism:
Homo sapiens (Human)
Description:
ChEMBL_820008
Residue:
469
Sequence:
MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL
  
Inhibitor
Name:
BDBM18351
Synonyms:
(2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-triol, 10 | (2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol | 1-Deoxynojirimycin | 1-deoxynojirimycin (DNJ) | CHEMBL307429 | US20230339856, Compound DNJ | US9181184, 1 | dNM
Type:
natural product
Emp. Form.:
C6H13NO4
Mol. Mass.:
163.1717
SMILES:
OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O
Structure:
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