Reaction Details Report a problem with these data
Target
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
Ligand
BDBM50179262
Substrate
n/a
Meas. Tech.
ChEMBL_325589 (CHEMBL860172)
Ki
4.11±n/a nM
Citation
 Berardi, F; Ferorelli, S; Abate, C; Pedone, MP; Colabufo, NA; Contino, M; Perrone, R Methyl substitution on the piperidine ring of N-[omega-(6-methoxynaphthalen-1-yl)alkyl] derivatives as a probe for selective binding and activity at the sigma(1) receptor. J Med Chem 48:8237-44 (2005) [PubMed]  Article 
Target
Name:
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
Synonyms:
EBP | EBP_CAVPO
Type:
PROTEIN
Mol. Mass.:
26684.52
Organism:
Cavia porcellus
Description:
ChEMBL_203193
Residue:
229
Sequence:
MATTSTGPLHPYWPRHLRLDHFVPNDLSAWYIVTVLFTVFGALVVTMWLLSSRASVVPLGTWRRLSVCWFAVCAFVHLVIEGWFVLYQKAILGDQAFLSQLWKEYAKGDSRYIIEDNFIICMESITVVLWGPLSLWAVIAFLRQHPSRYVLQFVISLGQIYGDLLYFLTEYRDGFQHGEMGHPIYFWFYFFFMNVLWLVIPGVLFFDSVKQFYGAQNALDTKVMKSKGK
  
Inhibitor
Name:
BDBM50179262
Synonyms:
1-(4-(6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)butyl)-4,4-dimethylpiperidine hydrochloride | CHEMBL540818
Type:
Small organic molecule
Emp. Form.:
C22H35NO
Mol. Mass.:
329.5194
SMILES:
COc1ccc2C(CCCCN3CCC(C)(C)CC3)CCCc2c1
Structure:
Search PDB for entries with ligand similarity: