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Target
Shikimate kinase
Ligand
BDBM50370962
Substrate
n/a
Meas. Tech.
ChEMBL_432675 (CHEMBL920649)
Kd
4390±n/a nM
Citation
 Han, C; Zhang, J; Chen, L; Chen, K; Shen, X; Jiang, H Discovery of Helicobacter pylori shikimate kinase inhibitors: bioassay and molecular modeling. Bioorg Med Chem 15:656-62 (2006) [PubMed]  Article 
Target
Name:
Shikimate kinase
Synonyms:
AROK_HELPY | SK | aroK
Type:
PROTEIN
Mol. Mass.:
18412.75
Organism:
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori)
Description:
ChEMBL_432674
Residue:
162
Sequence:
MQHLVLIGFMGSGKSSLAQELGLALKLEVLDTDMIISERVGLSVREIFEELGEDNFRMFEKNLIDELKTLKTPHVISTGGGIVMHENLKGLGTTFYLKMDFETLIKRLNQKEREKRPLLNNLTQAKELFEKRQALYEKNASFIIDARGGLNNSLKQVLQFIA
  
Inhibitor
Name:
BDBM50370962
Synonyms:
CHEMBL223867
Type:
Small organic molecule
Emp. Form.:
C27H23NO6S2
Mol. Mass.:
521.605
SMILES:
COc1cc(C=O)ccc1OCc1ccccc1COc1ccc(C=C2SC(S)=NC2=O)cc1OC |w:24.25,c:30|
Structure:
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