Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM50212662
Substrate
n/a
Meas. Tech.
ChEMBL_436709 (CHEMBL905018)
EC50
41±n/a nM
Citation
 Tan, ES; Miyakawa, M; Bunzow, JR; Grandy, DK; Scanlan, TS Exploring the structure-activity relationship of the ethylamine portion of 3-iodothyronamine for rat and mouse trace amine-associated receptor 1. J Med Chem 50:2787-98 (2007) [PubMed]  Article 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TAAR1_RAT | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1
Type:
Enzyme
Mol. Mass.:
38034.73
Organism:
Rattus norvegicus (Rat)
Description:
Q923Y9
Residue:
332
Sequence:
MHLCHNSANISHTNSNWSRDVRASLYSLISLIILTTLVGNLIVIISISHFKQLHTPTNWLLHSMAVVDFLLGCLVMPYSMVRTVEHCWYFGELFCKLHTSTDIMLSSASILHLAFISIDRYYAVCDPLRYKAKINLAAIFVMILISWSLPAVFAFGMIFLELNLEGVEELYHNQVFCLRGCFPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRANLQVGLEGESRAPQSKETKAAKTLGIMVGVFLLCWCPFFFCMVLDPFLGYVIPPTLNDTLNWFGYLNSAFNPMVYAFFYPWFRRALKMVLFGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM50212662
Synonyms:
2-(4-phenoxyphenyl)-4-phenylbut-3-yn-1-amine hydrochloride | CHEMBL229686
Type:
Small organic molecule
Emp. Form.:
C22H20NO
Mol. Mass.:
314.3998
SMILES:
[NH3+]CC(C#Cc1ccccc1)c1ccc(Oc2ccccc2)cc1 |w:2.2|
Structure:
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