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Target
Tissue alpha-L-fucosidase
Ligand
BDBM50214378
Substrate
n/a
Meas. Tech.
ChEMBL_437030 (CHEMBL906424)
IC50
83000±n/a nM
Citation
 Kato, A; Kato, N; Adachi, I; Hollinshead, J; Fleet, GW; Kuriyama, C; Ikeda, K; Asano, N; Nash, RJ Isolation of glycosidase-inhibiting hyacinthacines and related alkaloids from Scilla socialis. J Nat Prod 70:993-7 (2007) [PubMed]  Article 
Target
Name:
Tissue alpha-L-fucosidase
Synonyms:
Alpha-L-fucosidase I | Alpha-L-fucoside fucohydrolase | FUCA1 | FUCO_HUMAN | Tissue alpha-L-fucosidase
Type:
PROTEIN
Mol. Mass.:
53690.69
Organism:
Homo sapiens (Human)
Description:
ChEMBL_34088
Residue:
466
Sequence:
MRAPGMRSRPAGPALLLLLLFLGAAESVRRAQPPRRYTPDWPSLDSRPLPAWFDEAKFGVFIHWGVFSVPAWGSEWFWWHWQGEGRPQYQRFMRDNYPPGFSYADFGPQFTARFFHPEEWADLFQAAGAKYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYGLYHSLLEWFHPLYLLDKKNGFKTQHFVSAKTMPELYDLVNSYKPDLIWSDGEWECPDTYWNSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSIDKFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGKWLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTKITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK
  
Inhibitor
Name:
BDBM50214378
Synonyms:
CHEMBL376799 | beta-1-C-ethyl-1-deoxymannojirimycin
Type:
Small organic molecule
Emp. Form.:
C8H17NO4
Mol. Mass.:
191.2249
SMILES:
CC[C@@H]1N[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O
Structure:
Search PDB for entries with ligand similarity: