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Target
Amine oxidase [flavin-containing] A
Ligand
BDBM50217268
Substrate
n/a
Meas. Tech.
ChEMBL_440608 (CHEMBL889702)
IC50
>150000±n/a nM
Citation
 Hwang, JH; Hong, SS; Han, XH; Hwang, JS; Lee, D; Lee, H; Yun, YP; Kim, Y; Ro, JS; Hwang, BY Prenylated xanthones from the root bark of Cudrania tricuspidata. J Nat Prod 70:1207-9 (2007) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] A
Synonyms:
AOFA_MOUSE | Amine oxidase [flavin-containing] A | MAO-A | Maoa | Monoamine oxidase | Monoamine oxidase A | Monoamine oxidase type A
Type:
PROTEIN
Mol. Mass.:
59608.24
Organism:
Mus musculus
Description:
ChEMBL_122776
Residue:
526
Sequence:
MTDLEKPSITGHMFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWVDVGGAYVGPTQNRILRLSKELGIETYKVNVNERLVQYVKGKTYPFRGAFPPVWNPLAYLDYNNLWRTMDDMGKEIPVDAPWQARHAEEWDKITMKDLIDKICWTKTAREFAYLFVNINVTSEPHEVSALWFLWYVRQCGGTSRIFSVTNGGQERKFVGGSGQISEQIMVLLGDKVKLSSPVTYIDQTDDNIIIETLNHEHYECKYVISAIPPVLTAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAFWKKKDYCGCMIIEDEEAPISITLDDTKPDGSMPAIMGFILARKAERLAKLHKDIRKRKICELYAKVLGSQEALSPVHYEEKNWCEEQYSGGCYTAYFPPGIMTLYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALGKVAKKDIWVQEPESKDVPALEITHTFLERNLPSVPGLLKITGFSTSVALLCFVLYKFKQPQS
  
Inhibitor
Name:
BDBM50217268
Synonyms:
1,6,7-trihydroxy-3-methoxy-2,4-(3-methylbut-2-enyl)-xanthone | CHEMBL228335
Type:
Small organic molecule
Emp. Form.:
C24H26O6
Mol. Mass.:
410.4596
SMILES:
[#6]-[#8]-c1c(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])c2c(oc3cc(-[#8])c(-[#8])cc3c2=O)c1-[#6]\[#6]=[#6](\[#6])-[#6]
Structure:
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