Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50225156
Substrate
n/a
Meas. Tech.
ChEMBL_458570 (CHEMBL941883)
Ki
79±n/a nM
Citation
 Manera, C; Cascio, MG; Benetti, V; Allarà, M; Tuccinardi, T; Martinelli, A; Saccomanni, G; Vivoli, E; Ghelardini, C; Di Marzo, V; Ferrarini, PL New 1,8-naphthyridine and quinoline derivatives as CB2 selective agonists. Bioorg Med Chem Lett 17:6505-10 (2007) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50225156
Synonyms:
1-benzyl-N-cyclohexyl-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxamide | CHEMBL250767
Type:
Small organic molecule
Emp. Form.:
C24H26N2O3
Mol. Mass.:
390.4748
SMILES:
COc1ccc2c(c1)n(Cc1ccccc1)cc(C(=O)NC1CCCCC1)c2=O
Structure:
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